Table 3.
Multiple logistic regression analysis of risk factors associated with all vascular events, arterial events, and venous events*
| Risk factor | Odds ratio (95% confidence interval)
|
||
|---|---|---|---|
| All vascular events | Arterial events | Venous events | |
| Age (years) | 1.01 (0.99–1.03) | 1.04 (1.02–1.06)† | 0.99 (0.97–1.00) |
| Sex (female) | 0.51 (0.28–0.94)† | 0.45 (0.24–0.85)† | 1.01 (0.53–1.93) |
| Smoking | 0.88 (0.55–1.42) | 0.97 (0.56–1.67) | ND |
| Hypertension | 1.84 (1.18–2.86)† | 2.45 (1.51–3.97)† | ND |
| Diabetes mellitus | 1.40 (0.55–3.59) | 2.13 (0.82–5.58) | ND |
| SLE | 1.16 (0.71–1.90) | 1.42 (0.80–2.54) | 0.79 (0.46–1.34) |
| Family history of CVD | 1.30 (0.84–2.00) | 1.28 (0.77–2.12) | ND |
| Ethnic origin | 1.23 (0.70–2.10) | 1.65 (0.82–3.32) | ND |
| aPL‡ | 0.96 (0.63–1.47) | 0.88 (0.54–1.43) | 1.22 (0.76–1.95) |
| Anti-Hsp60 | 1.77 (0.90–3.46) | 2.26 (1.13–4.52)† | 1.25 (0.61–2.60) |
*
Analysis was performed on all cohort members with no missing values for any of the variables (n = 398 for all vascular events [arterial and venous combined] and for arterial vascular events; n = 399 for venous vascular events). ND = not determined (variables that were not entered into the model for venous vascular events) (see Table 1 for other definitions).
†
P < 0.05.
‡
Positivity for at least 1 of the following: IgG or IgM aCL (>40 phospholipid units), LAC, or anti-β2GPI.