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. 2012 Sep 10;109(39):15722–15727. doi: 10.1073/pnas.1206077109

Fig. 5.

Fig. 5.

Modeled reactive structure for the FDTS-dUMP-FAD-CH2H4folate intermediate complex. FAD’s isoalloxazine ring and His53 are rotated as in Fig. 4 and Fig. S5. The iminium-CH2H4folate intermediate is docked into the site as described in the main text. Chain A is colored in gray, chain C in purple, and chain D in wheat color.