Table 2.

Coupling of Aryl Halides with Secondary Alcohols^[a]

^[a]Reaction conditions: ArX (1 mmol), alcohol (2 mmol), Cs₂CO₃ (1.5 mmol), (allylPdCl)2 (0.5 – 2.5 mol %), L4 (1.5 – 6 mol %), toluene (1 mL), 90 °C, 21 h; isolated yields (average of two or more runs).

^[b]200 mg of 4Å molecular sieves was added.

^[c]in Bu₃N.

^[d]cyclohexanol (1.5 mmol) was used.

^[e]In Et₃N.

^[f]24 h.