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. Author manuscript; available in PMC: 2013 Nov 1.
Published in final edited form as: Chem Biol Drug Des. 2012 Sep 3;80(5):771–774. doi: 10.1111/cbdd.12003

Fig. 1.

Fig. 1

Dose-response curves of the effects of morphine and [Dmt1]DALDA in the paw withdrawal test of the rat. Radiant heat was applied to the right hind paws of naïve rats, and paw withdrawal latencies were measured. Paw withdrawal latency of each paw was determined as a mean of 3 measurements per paw. Paw withdrawal latencies were determined prior to (baseline latencies) and 30 or 120 min after subcutaneous administration of morphine or [Dmt1]DALDA, respectively (response latencies). The number of animals tested for each dose was 6. Data are shown as maximum possible effect (%MPE) (see text).