Table 1.
Summary of Subject Characteristics for Cohorts 1 and 2
| Cohort 1 |
Cohort 2 |
Total |
||||
|---|---|---|---|---|---|---|
| Control | Schizophrenia | Control | Schizophrenia | Control | Schizophrenia | |
| n | 15 | 15 | 12 | 12 | 27 | 27 |
| Mean Age (SD) | 46.8 (8.3) | 47.6 (5.5) | 45.1 (12.9) | 47.3 (13.4) | 46.0 (10.4) | 47.4 (9.6) |
| Range | 27–64 | 38–63 | 19–65 | 25–71 | 19–65 | 25–71 |
| Sex (F/M) | 6/9 | 6/9 | 4/8 | 4/8 | 10/17 | 10/17 |
| Handedness (R/L/A/U) | 10/4/0/1 | 7/3/1/4 | 11/1/0/0 | 6/2/1/3 | 21/5/0/1 | 13/5/2/7 |
| PMI (SD) | 13.9 (5.5) | 15.9 (6.6) | 18.0 (6.6) | 17.9 (8.8) | 15.7 (6.3) | 16.8 (7.6) |
| Storage Time, Months (SD) | 168 (29) | 167 (26) | 111 (27) | 102 (30) | 142 (40) | 138 (43) |
| Illness Duration, Years (SD) | 24.9 (5.6) | 22.1 (14.6) | 23.7 (10.6) | |||
| Range | 14–34 | 3–50 | 3–50 | |||
| Suicide, n (%) | 3 (20%) | 2 (17%) | 5 (19%) | |||
| Schizoaffective, n (%) | 3 (20%) | 4 (33%) | 7 (26%) | |||
| Living Independently ATOD, n (%) | 7 (47%) | 2 (17%) | 9 (33%) | |||
| Alcohol/Substance Abuse ATOD, n (%) | 9 (60%) | 7 (58%) | 16 (59%) | |||
| History of Cannabis Use, n (%) | 3 (20%) | 5 (42%) | 8 (30%) | |||
| Antipsychotic ATOD, n (%) | 13 (87%) | 11 (92%) | 24 (89%) | |||
| Benzodiazepine ATOD, n (%) | 1 (7%) | 5 (33%) | 1 (8%) | 1 (4%) | 6 (22%) | |
| Anticonvulsant ATOD, n (%) | 3 (20%) | 4 (33%) | 7 (26%) | |||
| Antidepressant ATOD, n (%) | 5 (33%) | 4 (33%) | 9 (33%) | |||
Each subject in cohorts 1 and 2 was previously matched to a normal comparison subject based on sex and as closely as possible for age and postmortem interval and group matched for handedness. There were no diagnostic group differences in age [t(52) = .517, p = .608] or postmortem interval [t(52) = .584, p = .561] or in the distribution of handedness between diagnostic groups (χ12 = 1.46, p = .314). Mean storage time did not differ between diagnostic groups [cohort 1: t(28) = .040, p = .968; cohort 2: t(22) = .596, p = .557].
A, ambidextrous; ATOD, at time of death; F, female; L, left-handed; M, male; PMI, postmortem interval; R, right-handed; U, unknown.