Table 3.

Biodistribution of 8β-(2-[¹⁸F]Fluoroethyl)estradiol [¹⁸F]6in Immature Female Sprague Dawley Rats with Letrozole and PMSG treatments.

	percentage injected dose/gram ±SDa (n = 5)
	1 h	1 h (E2 blocked)b	1 h (DPN blocked)c	1 h (PPT blocked)d
blood	0.23 ± 0.07	0.19 ± 0.02	0.17 ± 0.03	0.16 ± 0.03
lung	0.41 ± 0.02	0.38 ± 0.04	0.36 ± 0.05	0.36 ± 0.06
liver	1.67 ± 0.31	1.51 ± 0.13	1.41 ± 0.22	1.40 ± 0.12
spleen	0.13 ± 0.16	0.12 ± 0.07	0.12 ± 0.01	0.12 ± 0.02
kidney	0.66 ± 0.12	0.55 ± 0.08	0.59 ± 0.11	0.51 ± 0.09
muscle	0.14 ± 0.03	0.12 ± 0.01	0.13 ± 0.02	0.12 ± 0.02
fat	0.49 ± 0.12	0.50 ± 0.11	0.53 ± 0.18	0.53 ± 0.16
heart	0.17 ± 0.03	0.14 ± 0.01	0.15 ± 0.02	0.14 ± 0.02
bone	0.40 ± 0.10	0.33 ± 0.02	0.37 ± 0.07	0.34 ± 0.05
uterus	0.26 ± 0.07	0.20 ± 0.04	0.22 ± 0.03	0.19 ± 0.02
ovaries	0.34 ± 0.04	0.30 ± 0.06	0.32 ± 0.10	0.30 ± 0.05
thymus	0.10 ± 0.01	0.10 ± 0.01	0.09 ± 0.02	0.08 ± 0.01

^aSD is standard deviation. Rats were injected via the tail vein with 18 μCi of [¹⁸F]6.

^bDose includes estradiol (20 μg).

^cDose includes DPN (200 μg).

^dDose includes PPT (200 μg).