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. Author manuscript; available in PMC: 2013 Nov 1.
Published in final edited form as: Nucl Med Biol. 2012 Jun 30;39(8):1105–1116. doi: 10.1016/j.nucmedbio.2012.05.011

Table 4.

Biodistribution of [76Br]Br-ERB-041in Immature Female Mice

percentage injected dose/gram ±SDa (n = 3)
1 h
(low dose)b 		1 h
(high dose)b 		1 h
(high dose,
E2blocked)b,c 		3 h
(high
dose)b 		3 h
(high dose,
E2blocked)b,c 		6 h
(high dose) b
blood 0.40 ± 0.12 0.36 ± 0.14 0.41 ± 0.10 0.21 ± 0.06 0.19 ± 0.08 0.09 ± 0.01
lung 0.33 ± 0.05 0.27 ± 0.09 0.34 ± 0.11 0.17 ± 0.03 0.15 ± 0.05 0.08 ± 0.01
liver 0.54 ± 0.19 0.40 ± 0.16 0.51 ± 0.12 0.36 ± 0.09 0.28 ± 0.10 0.14 ± 0.02
spleen 0.13 ± 0.01 0.08 ± 0.03 0.09 ± 0.02 0.05 ± 0.01 0.05 ± 0.02 0.03 ± 0.00
kidney 1.06 ± 0.38 1.58 ± 0.78 0.93 ± 0.23 0.82 ± 0.16 0.64 ± 0.25 0.30 ± 0.12
muscle 0.23 ± 0.13 0.07 ± 0.02 0.18 ± 0.13 0.05 ± 0.01 0.04 ± 0.02 0.03 ± 0.01
uterus 0.26 ± 0.09 0.21 ± 0.10 0.33 ± 0.22 0.09 ± 0.02 0.13 ± 0.02 0.09 ± 0.03
ovaries 0.35 ± 0.03 0.19 ± 0.05 0.30 ± 0.15 0.10 ± 0.02 0.10 ± 0.04 0.07 ± 0.02
a

SD is standard deviation.;

b

Mice were injected via the tail vein with 0.5 μCi (low dose) or 3-4 μCi (highdose).;

c

Dose includes estradiol (E2, 20 μg).