Figure 2. Monitored progression of luminescence for Ub-AML and Z-RLRGG-Glo.
Increasing concentrations (indicated) of UCHL3 were incubated with either 500nM Ub-AML (A) or 20μM Z-RLRGG-AML(C) with immediate and continuous monitoring of luminescence (RLUs). Calculated S/B values (see methods) are shown for Ub-AML (B) and Z-RLRGG-AML(D), with the dashed line drawn to illustrate S/B = 3. Data are representative of triplicate measurements.