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. 2012 Oct 5;11(4):529–540. doi: 10.1016/j.stem.2012.06.017

Figure 7.

Figure 7

The Par Complex and Integrins Direct Asymmetric Cell Division in ISCs

(A and B) Adult Drosophila ISCs divide asymmetrically through Integrin-dependent asymmetric localization the Par complex during mitosis. Different fates might arise either because the two daughter cells reside in different microenvironments and receive different signals (A) or because levels of aPKC activity are higher in one of the two daughter cells (B).