Table II.
HHV-8 shedding rates and quantities detected in oropharyngeal swabs collected among participants completing both study arms, for A. by study arms, and B. by HAART use.
A) | ||||
---|---|---|---|---|
Total (n=58) | Placebo (n=58) | Valacyclovir (n=42) | Famciclovir (n=16) | |
Overall frequency of HHV-8 detection, oropharyngeal swabs with HHV-8 detected/all swabs (%) | 1128/6036 (19) | 618/2992 (21) | 323/2221 (15) | 187/823 (23) |
Person-level frequency (%)of HHV-8 detection, median (IQR) | 2 (0–23) | 2 (0 – 34) | 2 (0 – 10) | 0 (0 – 51) |
HHV-8 DNA quantity* (log10 copies/mL), median (IQR) | 4.68 (3.67–5.72) | 4.44 (3.61–5.31) | 5.26 (3.80–6.3) | 4.68 (3.80–5.56) |
B) | ||
---|---|---|
HAART (n= 17) | No HAART (n= 41) | |
Overall frequency of HHV-8 detection, oroparyngeal swabs with HHV-8 detected/all swabs (%) | 93/1761 (5) | 1034/4074 (25) |
Person-level frequency (%) of HHV-8 detection, median (IQR) | 0 (0, 2) | 4 (0, 38) |
HHV-8 DNA quantity* (log10 copies/mL), median (IQR) | 4.62 (3.42–5.53) | 4.69 (3.67–5.73) |
On days with detectable HHV-8