Figure 3.
Uptake of doxorubcin in MCF-7 cells. MCF-7 cells were incubated with ELP-DOXO, Bac-ELP-DOXO, Tat-ELP-DOXO, and SynB1-ELP-DOXO (10 μM in cell culture media) for 1 h at either 37 °C or 42 °C. Dox fluorescence intensity was determined using flow cytometry and is expressed in relative fluorescence units (RFU). * indicates statistical significance between ELP-DOXO at 42 °C and both Tat- and SynB1-ELP-DOXO at 42 °C (p < 0.01). The data represents the mean of 3 experiments (error bars, SEM).