Skip to main content
. 2012 Oct 1;26(19):2192–2205. doi: 10.1101/gad.192666.112

Figure 3.

Figure 3.

The effect of Med23 deficiency on SRF target gene expression. (A) Gene profiling of wild-type (WT) and Med23 knockout MEFs with or without serum induction (30 and 90 min). The degree of induction is reflected by relative color coding. (Green) Low expression; (red) high expression. SRF target muscle lineage genes or growth-related genes were assigned different colors (red or green). (B) The relative expression of known RhoA/MAL or Ras/ELK1 targets in MEFs at 30 min after serum stimulation was extracted from the microarray data. The expression levels of two sets genes in knockout MEFs were normalized to 1. (C) The relative expression of the two sets genes in wild-type, knockout, and KO+Med23 MEFs at 30 min after serum stimulation was analyzed by real-time PCR, with the expression in KO+Med23 MEFs normalized to 1.