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. Author manuscript; available in PMC: 2012 Oct 8.
Published in final edited form as: Cardiovasc Hematol Agents Med Chem. 2012 Sep;10(3):265–274. doi: 10.2174/187152512802651051
Endothelial cell type or
vascular bed		 Role of TRPC3 Reference
Porcine coronary endothelial (PCAEC); uterine endothelial (UAEC) Ca2+ influx underlying nitric oxide release [94, 95]
Human pre-glomerular endothelium Increased expression in patients with malignant hypertension [92]
Human kidney vascular endothelium Increased expression in renal cell carcinoma patients with history of hypertension [93]
Human coronary artery endothelial (HCAEC) Regulated expression of VCAM-1; monocyte recruitment; NFkB signaling [25, 28]
Pulmonary aortic endothelial (PAEC) Forms redox sensitive channels; normal and oxidative stress-induced depolarization [22, 83]
Calf vascular endothelial Oxidative stress induced membrane depolarization [85]