Table 1.
Comparison of the stem cell sources.
| Cord Blood | PB | BM | |
|---|---|---|---|
| Risk for the donor | None | Yes | Yes |
|
| |||
| Duration of searching (month) | ≤1 | 3–6 | 3–6 |
|
| |||
| Factors limiting the engraftment | Cell count | HLA match | HLA match |
|
| |||
| Dominant factor affecting the outcome | Engraftment failure delayed immune recovery |
GVHD | GVHD |
|
| |||
| Minimal HLA match | 4/6 | 9/10 | 9/10 |
|
| |||
| Risk for GVHD | Low | High | High |
| Acute | Low | High | High |
| Chronic | Low | Higher | High |
|
| |||
| DLI possibility | None | Possible | Possible |
|
| |||
| Posttransplant infection risk | Higher | High | High |
|
| |||
| Immunotheraphy possibility | None | Yes | Yes |