Table 1.

Comparisons of mean angiogenesis and fibrogenesis regulatory factor levels in proliferative diabetic retinopathy (PDR), proliferative vitreoretinopathy (PVR), and rhegmatogenous retinal detachment (RD) patients.

Disease group	OPN (ng/mL)	HMGB1 (ng/mL)	CTGF (ng/mL)	PEDF (ng/mL)
PDR (n = 48)	837.36 ± 1012.3	4.47 ± 10.1	1.91 ± 2.2	4.06 ± 7.9
RD (n = 30)	209.33 ± 192.5	0.98 ± 0.9	0.22 ± 0.3	0.32 ± 0.2
P value (Mann-Whitney test)	<0.001*	0.002*	<0.001*	<0.001*
PVR (n = 17)	737.95 ± 996.5	2.79 ± 5.4	0.65 ± 0.5	0.98 ± 0.9
RD (n = 30)	209.33 ± 192.5	0.98 ± 0.9	0.22 ± 0.3	0.32 ± 0.2
P value (Mann-Whitney test)	0.425	0.571	<0.001*	<0.004*

*Statistically significant at 5% level of significance.

OPN: osteopontin; HMGB1: high-mobility group box-1; CTGF: connective tissue growth factor; PEDF: pigment epithelium-derived factor.