Table 3.
Comparisons of mean angiogenesis and fibrogenesis regulatory factor levels in proliferative diabetic retinopathy (PDR) patients with or without traction retinal detachment (TRD).
| Disease group | OPN (ng/mL) | HMGB1 (ng/mL) | CTGF (ng/mL) | PEDF (ng/mL) |
|---|---|---|---|---|
| PDR with TRD (n = 21) | 584.15 ± 910.9 | 4.08 ± 6.9 | 1.38 ± 1.9 | 3.18 ± 5.5 |
| PDR without TRD (n = 27) | 868.2 ± 962.6 | 4.57 ± 10.7 | 1.94 ± 2.1 | 3.94 ± 8.4 |
| RD (n = 30) | 209.33 ± 192.5 | 0.98 ± 0.9 | 0.22 ± 0.3 | 0.32 ± 0.2 |
| ANOVA P value | 0.002* | 0.003* | <0.001* | <0.001* |
*Statistically significant at 5% level of significance.
OPN: osteopontin; HMGB1: high-mobility group box-1; CTGF: connective tissue growth factor; PEDF: pigment epithelium-derived factor; RD: rhegmatogenous retinal detachment.