Table 3.
Outcome Variables After Preoperative Versus Postoperative Concurrent Chemoradiation for Superior Sulcus Tumors
| Outcome Variables | Preoperative Concurrent Chemoradiation | Postoperative Concurrent Chemoradiation, Current Study | |
|---|---|---|---|
| SWOG 94–16 | JCOG 9806 | ||
| Adherence to treatment regimen | 75%a | 76% | 78% |
| Operative mortality rates | 2.4% | 3.5% | 0% |
| R0/R1 resection rates | 92%b | 95% | 100% |
| Locoregional control rates | 85%c | 87%d | 76% |
| 5-year overall survival rates | 44% | 56% | 50% |
Abbreviations: JCOG, Japan Clinical Oncology Group; SWOG, Southwest Oncology Group.
a
Defined as percentage of patients undergoing induction chemoradiation followed by thoracotomy as a proportion of the total number of eligible patients.
b
Defined as percentage of patients in whom R0/R1 resection was achieved as a proportion of those patients who proceeded to surgery.
c
Reported as local control.
d
Reported as initial site of failure.