Table 2.
Spectral-domain (SD) optical coherence tomography retinal nerve fibre layer (RNFL) thickness reproducibility in healthy participants and patients
| Healthy participants |
Patients |
|||||||
|---|---|---|---|---|---|---|---|---|
| Mean RNFL thickness (μm) (95% Cl) | Sw (1.96 SE) | CV% | ICC (95% Cl) | Mean RNFL thickness (μm) (95% Cl) | Sw (1.96 SE) | CV% | ICC (95% Cl) | |
| Temporal | 65.8 (60.7 to 70.9) | 1.5 (0.33) | 2.3 | 0.98 (0.97 to 0.99) | 58.3 (55.8 to 60.8) | 1.6 (0.51) | 2.7 | 0.94 (0.91 to 0.96) |
| Superior | 110.9 (106.1 to 115.6) | 2.8 (0.71) | 2.6 | 0.93 (0.89 to 0.96) | 93.1 (89.1 to 97) | 2.2 (0.33) | 2.5 | 0.98 (0.97 to 0.99) |
| Nasal | 70.2 (66.2 to 74.3) | 2.9 (0.79) | 4.4 | 0.90 (0.83 to 0.94) | 66.1 (63.8 to 68.4) | 2.4 (0.4) | 3.7 | 0.92 (0.89 to 0.95) |
| Inferior | 112.4 (107 to 117.7) | 2.6 (0.69) | 2.3 | 0.95 (0.92 to 0.98) | 96.4 (91.8 to 101.1) | 2.8 (0.58) | 3.1 | 0.97 (0.95 to 0.98) |
| Average | 89.8 (86.6 to 93) | 1.3 (0.38) | 1.5 | 0.96 (0.94 to 0.98) | 78.4 (76 to 81) | 1.2 (0.19) | 1.6 | 0.98 (0.97 to 0.99) |
| 1-o'clock | 98.8 (93 to 104.6) | 4.9 (1.97) | 5 | 0.81 (0.69 to 0.89) | 84.1 (80.2 to 88.1) | 3.6 (0.51) | 4.3 | 0.94 (0.92 to 0.96) |
| 2-o'clock | 82.7 (75.9 to 89.4) | 5 (1.57) | 6.6 | 0.88 (0.80 to 0.94) | 78.6 (74.6 to 82.6) | 3.5 (0.6) | 4.8 | 0.94 (0.92 to 0.96) |
| 3-o'clock | 61.2 (57.6 to 64.8) | 2.4 (0.76) | 4.2 | 0.90 (0.83 to 0.94) | 59.4 (57 to 61.9) | 3 (0.49) | 5.1 | 0.89 (0.85 to 0.93) |
| 4-o'clock | 66.8 (61.6 to 72) | 3.3 (0.61) | 4.9 | 0.94 (0.89 to 0.97) | 60.2 (57.8 to 62.6) | 3 (0.52) | 5 | 0.88 (0.83 to 0.92) |
| 5-o'clock | 92.4 (83.8 to 100.9) | 4 (0.81) | 4.1 | 0.97 (0.94 to 0.98) | 82.4 (78.5 to 86.3) | 3.9 (0.73) | 4.9 | 0.92 (0.88 to 0.94) |
| 6-o'clock | 121.5 (114.8 to 128.2) | 4.3 (1.34) | 3.5 | 0.91 (0.84 to 0.95) | 103.3 (97.4 to 109) | 4.9 (1.06) | 5.2 | 0.94 (0.91 to 0.96) |
| 7-o'clock | 123.2 (112.2 to 134.3) | 4.4 (0.94) | 3.6 | 0.97 (0.95 to 0.99) | 103.5 (96 to 111.1) | 4.1 (0.85) | 4.5 | 0.97 (0.96 to 0.98) |
| 8-o'clock | 70.3 (62.4 to 78.3) | 2.7 (0.78) | 3.6 | 0.97 (0.95 to 0.99) | 58.1 (55.3 to 60.9) | 2.4 (0.65) | 4 | 0.91 (0.88 to 0.94) |
| 9-o'clock | 50.6 (47.3 to 54) | 1.1 (0.24) | 2.3 | 0.98 (0.96 to 0.99) | 48.1 (45.6 to 50.5) | 1.6 (0.94) | 2.9 | 0.84 (0.78 to 0.89) |
| 10-o'clock | 76.4 (70.1 to 82.6) | 2.3 (0.76) | 3.1 | 0.97 (0.94 to 0.98) | 68.6 (64.9 to 72.3) | 2.2 (0.47) | 3.3 | 0.97 (0.95 to 0.98) |
| 11-o'clock | 120.6 (111.8 to 129.4) | 4.3 (0.85) | 3.7 | 0.96 (0.93 to 0.98) | 104.2 (99 to 109.4) | 4.4 (0.78) | 4.6 | 0.94 (0.92 to 0.96) |
| 12-o'clock | 113.2 (105.6 to 120.8) | 4.4 (1.01) | 3.9 | 0.94 (0.90 to 0.97) | 90.7 (84.8 to 96.6) | 4.1 (0.86) | 5 | 0.95 (0.93 to 0.97) |
CV, coefficient of variation; ICC, intraclass correlation coefficient; Sw, within-subjects SD.