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. Author manuscript; available in PMC: 2012 Oct 8.
Published in final edited form as: Ophthalmology. 2008 Nov 17;116(1):14–24. doi: 10.1016/j.ophtha.2008.08.030

Figure 4.

Figure 4

This eye was classified as stable by Moorfields regression analysis (MRA), topographic change analysis (TCA), and trend analysis (TA), with all graders agreeing on no progression. However, glaucomatous progression was detected by the appearance of a new retinal nerve fiber layer (RNFL) defect in the inferotemporal region in the 2007 stereophotograph, in addition to the preexisting defect in the superotemporal region (both RNFL defects are indicated by the 2 arrows pointing towards each other at the boundary of the RNFL defect). This new RNFL defect can be detected on the HRT MRA and TCA (though not as a statistically significant change), but did not result in classification of progressed by any grader. The TA is based on the normalized “average” parameter defined as the average of several HRT parameters combined (rim area, rim volume, cup volume, cup shape, mean RNFL thickness, mean height of contour, mean contour elevation, contour line modulation temporal, mean cup depth and mean height inside contour line). HRT = Heidelberg Retina Tomograph.