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. Author manuscript; available in PMC: 2012 Oct 8.
Published in final edited form as: Am J Ophthalmol. 2009 Mar 9;147(6):1067–1074.e1. doi: 10.1016/j.ajo.2008.12.032

TABLE 2.

Reproducibility of RTVue Retinal Nerve Fiber Layer Thickness Measurements in Healthy Participants and Glaucoma Patients

RNFL
Parameters
Healthy Participants Glaucoma Patients


Mean (95% CI) Sw ± 1.96 se CV % ICC (95% CI) Mean (95% CI) Sw ± 1.96 se CV % ICC (95% CI)
TEMP (µm) 80.6 (77.4 to 83.8) 2.82 ± 0.52 3.54 0.92 (0.88 to 0.95) 71.2 (68.7 to 73.8) 3.36 ± 0.7 4.72 0.86 (0.81 to 0.91)
SUP (µm) 120.6 (117 to 124.3) 3.8 ± 0.57 3.16 0.91 (0.86 to 0.94) 103.2 (99.6 to 106.8) 3.67 ± 0.59 3.53 0.93 (0.89 to 0.95)
NAS (µm) 75.8 (72.9 to 78.7) 2.94 ± 0.44 3.88 0.91 (0.86 to 0.94) 68.6 (66.2 to 71.1) 3.22 ± 0.52 4.6 0.88 (0.83 to 0.92)
INF (µm) 134.3 (129.7 to 138.9) 3.53 ± 0.55 2.65 0.95 (0.92 to 0.97) 113.2 (108.9 to 117.4) 3.21 ± 0.48 2.87 0.96 (0.94 to 0.97)
AVG (µm) 102.8 (100.1 to 105.6) 1.57 ± 0.27 1.54 0.97 (0.95 to 0.98) 89.1 (86.5 to 91.7) 1.69 ± 0.23 1.9 0.97 (0.96 to 0.98)

AVG = average quadrant; CI = confidence interval; CV = coefficient of variation; ICC = intraclass correlation coefficient; INF = inferior quadrant; NAS = nasal quadrant; SUP = superior quadrant; Sw = within-subjects standard deviation; RNFL = retinal nerve fiber layer; TEMP = temporal quadrant.

Reproducibility is expressed as the Sw, the ICC, and the CV. Sw is defined as the square root of the within-subject variance (defined as the within-subjects sum of squares divided by its degrees of freedom). CV is calculated as the square root of the residual mean squared values of 3 measures, divided by mean.