TABLE 5.

Change in values from baseline to month 3 by atorvastatin dose

		Atorvastatin dose
		10 mg		20 mg		40 mg		80 mg
Variable	P	T/A	A	T/A	A	T/A	A	T/A	A
HDL-C (mg/dl)	<0.001	30 ± 14.4n = 3,100	0.5 ± 6.1n = 3,180	28.2 ± 14.3n = 1,964	0.2 ± 6.0n = 1,961	28.4 ± 14.4n = 1,447	0.5 ± 6.3n = 1510	28.0 ± 14.1n = 745	1.1 ± 6.9n = 663
LDL-C (mg/dl)	0.195	− 21.7 ± 20.0n = 3,090	0.8 ± 15.4n = 3,170	− 20.8 ± 22.1n = 1,954	0.5 ± 16.6n = 1,955	− 21.6 ± 21.2n = 1,443	0.6 ± 16.8n = 1,504	− 20.4 ± 23.6n = 740	0.1 ± 18.6n = 659
ApoA-I (mg/dl)	<0.001	26.4 ± 24.3n = 3,059	1.5 ± 21.7n = 3,135	24.8 ± 29.2n = 1,929	1.1 ± 17.7n = 1,934	24.2 ± 20.1n = 1,426	1.4 ± 14.1n = 1,497	24.4 ± 17.5n = 736	1.4 ± 14.1n = 652
ApoB (mg/dl)	0.225	− 12,9 ± 18.4n = 3,060	2.1 ± 15.9n = 3,060	− 11.8 ± 20.8n = 1,929	1.9 ± 17.5n = 1,934	− 13.1 ± 17.9n = 1,425	2.0 ± 16.7n = 736	− 11.6 ± 20.2n = 736	1.1 ± 16.5n = 652
Systolic BP (mm Hg)	0.121	4.8 ± 12.2n = 3,135	0.3 ± 10.7n = 3,207	4.1 ± 11.4n = 1,973	0.4 ± 10.5n = 1,972	4.0 ± 11.5n = 1,460	0.7 ± 10.2n = 1,517	4.9 ± 12.3n = 749	0.4 ± 11.0n = 667
Potassium (mmol/l)	0.325	− 0.1 ± 0.4n = 3,081	0.0 ± 0.4n = 3,155	− 0.1 ± 0.4n = 1,955	0.0 ± 0.4n = 1,950	− 0.1 ± 0.4n = 1,440	0.0 ± 0.4n = 1,502	− 0.1 ± 0.4n = 742	0.0 ± 0.4n = 659
Sodium (mmol/l)	0.109	0.6 ± 3.3n = 3,099	− 0.1 ± 3.1n = 3,168	0.6 ± 3.3n = 1,963	0.0 ± 3.2n = 1,960	0.6 ± 3.1n = 1,447	0.1 ± 3.1n = 1,509	0.4 ± 3.1n = 744	0.0 ± 3.1n = 662
Bicarbonate (mmol/l)	0.571	0.9 ± 3.7n = 3,089	0.6 ± 3.8n = 3,163	0.8 ± 3.3n = 1,954	0.5 ± 3.4n = 1,956	0.7 ± 3.4n = 1,444	0.6 ± 3.3n = 1,504	0.9 ± 3.2n = 740	0.5 ± 3.2n = 661
Aldosterone(ng/dl))	0.214	0.4 ± 6.5n = 863	0.3 ± 5.2n = 800	0.7 ± 5.3n = 607	− 0.4 ± 8.0n = 527	0.8 ± 5.5n = 399	0.2 ± 5.7n = 404	0.4 ± 7.3n = 188	0.0 ± 6.6n = 170
CRP (mg/l)	0.461	0.0 (− 0.5, 0.6)n = 3,074	0.0 (− 0.6, 0.6) n = 3,149	0.1 (− 0.3, 0.7)n = 1,944	0.1 (− 0.4, 0.7)n = 1,943	0.0 (− 0.4, 0.5)n = 1,439	0.0 (− 0.5, 0.5)n = 1497	0.0 (− 0.4, 0.5)n = 737	0.0 (− 0.6, 0.5)n = 656

Mean ± SD, except for C-reactive protein (CRP) values that are medians (interquartile range). P values indicate the test of heterogeneity across the atorvastatin doses. T/A, torcetrapib plus atorvastatin; A, atorvastatin alone.