Table 2.

Slope Analyses on Montgomery-Asberg Depression Rating Scale (MADRS) Total Score at Week 2 for Patients Showing a Response at Endpoint (≥ 50% reduction in MADRS total score)

	Slope Estimate (95% CI)
	Adjunctive Placebo	Adjunctive Aripiprazole	Difference of Slope Estimates
Moderate responders (≥ 50% and < 75%)	n = 79	n = 125	−0.7 (–1.5 to 0.1)
	−4.1 (–4.7 to –3.5)	−4.8 (–5.3 to –4.3)
Robust responders (≥ 75%)	n = 39	n = 77	−1.5 (–3.0 to 0.1)
	−5.6 (–6.9 to –4.4)	−7.1 (–8.0 to –6.2)
All responders (≥ 50%)a	n = 118	n = 202	−1.0 (–1.8 to –0.3)
	−4.6 (–5.2 to –4.0)	−5.7 (–6.1 to –5.2)

^aIncludes patients exhibiting a ≥ 50% reduction in MADRS total score at week 6.