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. Author manuscript; available in PMC: 2013 Oct 1.
Published in final edited form as: Curr Psychiatry Rep. 2012 Oct;14(5):469–477. doi: 10.1007/s11920-012-0300-0

Table 1.

Summary of psychosocial treatment studies for PTSD-SUD

Citation Sample n Treatment Control group Main findings
Boden et al. [47] Male veterans in VA SUD clinic 98 Seeking safety plus treatment as Usual Treatment as usual - No group differences in PTSD or alcohol use
- Seeking safety group decreased illicit drug use
Brady et al. [56] Treatment-seeking individuals 39 Concurrent treatment of PTSD and cocaine dependence None - Treatment gains in PTSD and cocaine use that were maintained at 6-months post-treatment
Donovan et al. [48] Male veterans 46 Transcend None - Improvements in PTSD and SUD outcomes
Hien et al. [45] Women recruited from community and clinical settings 107 Seeking safety Relapse prevention - Equal improvements in both conditions
Hien et al. [44•] Women in community SUD treatment programs 353 Seeking safety Women's health education - Equal improvements in both conditions
Lynch et al. [43] Incarcerated women 114 Seeking safety Waitlist - Seeking safety related to improvement in PTSD and depressive symptoms
McGovern et al. [50] Individuals receiving intensive outpatient SUD treatment 53 Integrated cognitive-behavioral therapy (I-CBT) Individual addiction counseling - I-CBT related to greater improvements in PTSD and SUD outcomes
- PTSD symptoms severity did not differ between groups at 6-month follow-up
Najavits et al. [58] Male community sample 5 Seeking safety plus exposure therapy None - Improvements in PTSD and SUD
- Exposure rated as most useful treatment component by patients
Norman et al. [42] Male OIF/OEF veterans 9 Seeking safety None - Seeking safety related to improvement in PTSD and depressive symptoms
- 5 participants decreased number of drinking days
Triffleman [54] Primarily cocaine-abusing patients 12 Substance dependence PTSD therapy 12-Step facilitation - PTSD symptoms decreased during treatment for both groups
- Substance use decreased over follow-up
Zlotnick et al. [46] Incarcerated women 49 Seeking safety plus Treatment as usual Treatment as usual - Equal improvements in both conditions