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. Author manuscript; available in PMC: 2013 Mar 27.
Published in final edited form as: Nature. 2012 Sep 9;489(7417):519–525. doi: 10.1038/nature11404

Figure 4. Multi-faceted characterization of mechanisms of CDKN2A loss.

Figure 4

a, Schematic view of the exon structure of CDKN2A demonstrating the types of alterations identified in the study. The locations of point mutation are denoted by black and green circles. b, CDKN2A expression (y-axis) versus CDKN2A copy number (x-axis). Samples are represented by circles and colored-coded by specific type of CDKN2A alteration. c, Diagram of the KIAA1797-CDKN2A fusion identified by whole genome sequencing. d, CDKN2A alterations and expression levels (binary) in each sample.