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. Author manuscript; available in PMC: 2013 Apr 12.
Published in final edited form as: Neuron. 2012 Apr 12;74(1):65–78. doi: 10.1016/j.neuron.2012.01.031

Figure 6. Clonal knockdown of dla reveals intra-lineage Notch signaling in daughter cells of asymmetric division.

Figure 6

(A) A schematic depicting two different modes of Notch signaling. Left: lateral inhibition. Right: Intra-lineage. (B) Overview of the transplantation strategy. (C) Representative image of a single 4-cell clone. Inset is the enlargement of the area highlighted by the red dashed box. (D) Representative images of two single clones in control morpholino group (top) and dla morpholino group (bottom). In control, two single 4-cell clones contain one progenitor and three neuronal granddaughter cells. In the dla morpholino group, two single 4-cell clones contain four neuronal granddaughter cells. (E) Quantification for D. ** p < 0.01, *** p < 0.001 vs Ctrl MO, z-test. See also Figure S5.