Table 2.

Baseline parameters of arterial blood gas in anesthetized rats exposed to VEH and SH

	VEH	SH 2h	SH D5
Paco2 (torr)	36.8 ± 2.7	41.8 ± 0.5	36.8 ± 2.8
Sao2 (%)	93.5 ± 0.5	87.5 ± 3.3	92.5 ± 1.9
pH (unit)	7.41 ± 0.02	7.22 ± 0.04*	7.43 ± 0.03†
HCO3− (mM)	22.6 ± 1.5	15.9 ± 1.4*	24.5 ± 0.5†
BE (mM)	−0.4 ± 1.4	−10.8 ± 2.1*	0.6 ± 0.5†

SH 2h and SH D5 represent the data obtained at 2 h and on day 5 after high-dose (SH, 4.0 mg h m⁻³) exposures.

^*P < 0.05, compared to VEH

^†P < 0.05, compared to SH 2h. Paco₂, arterial CO₂ partial pressure; Sao₂, arterial O₂ saturation; HCO₃⁻, bicarbonate; BE, base excess.