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. Author manuscript; available in PMC: 2012 Oct 8.
Published in final edited form as: J Med Chem. 2011 Jun 2;54(13):4350–4364. doi: 10.1021/jm2001025

Figure 6.

Figure 6

The isoxazole HDAC inhibitor/probe 2b induces apoptosis in HepG2 cells independent of p53 acetylation: A. Western blotting to detect the activation of caspase 3 and the acetylation of p53 in the treated HepG2 cells; B. Histograms representing the acetylation of p53 protein in the cell extracts.