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. 2012 Oct 8;7(10):e47007. doi: 10.1371/journal.pone.0047007

Figure 3. Collagen/elastin content ratio quantification in the ovarian stroma.

Figure 3

(A) Representative merges of TPEF (green) and SHG (red) cross-sectional images of ovarian tissues obtained from H&E-stained samples. All scale bars are 20 µm. (B) SAAID index. Each bar represents the mean ±S.D. of independent measurements from stroma regions of image A. The total number of regions from which values were extracted was normal (n = 15), serous (adenoma: n = 12, borderline: n = 9, adenocarcinoma: n = 33) and mucinous (adenoma: n = 12, borderline: n = 9, adenocarcinoma: n = 12). Asterisks indicate a significant increase as compared to the non-tumor tissues (p<0.05, t-test).