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. 2012 Oct 8;7(10):e47012. doi: 10.1371/journal.pone.0047012

Table 2. Association of clinical-pathological characteristics and hypermethylation/LOH status of the WNT7A gene in clear cell RCCs.

Parameters Methylated p*-value LOH
Age <50 38% (5/13) 0.012 86% (6/7)
>50 77% (24/31) 85% (17/20)
Fuhrman nuclear grades 1–2 55%(16/29) 0.037 94% (16/17)
Fuhrman nuclear grades 3–4 87%(13/15) 70% (7/10)
Stages I–II 53%(17/32) 0.003 89% (16/18)
Stages III–IV 100%(12/12) 78% (7/9)
*

p-value is referred to correlation between clinical-pathological characteristics and hypermethylation status.