Table 3. Gene Onthology Analysis of the differentially expressed genes following MYBBP1A-down-regulation in HeLa cells.

GO Term	N. genes	%	p-value
Cell cycle	72	9.3	1.4E−10
Mitosis	27	3.5	1.3E−6
Cell cycle arrest	15	1.9	8.0E−5
Chromosome segregation	17	2.2	1.5E−7
Sister chromatid exchange	12	1.6	1.7E−7
Chromosome condensation	16	2.1	2.0E−4
Spindle	17	2.2	2.7E−4
Response to DNA damage	37	4.8	1.8E−6
Apoptosis	46	6.0	7.8E−5
Microtubule organizing center	25	3.2	8.1E−5
Centrosome	23	3.0	9.6E−5
Chromatin	21	2.7	1.5E−4
Cellular response to stress	52	6.7	1.1E−7

N = total number of differentially expressed genes within the GO cathegory.

%: percent of the total number of differentially expressed genes.

p-value: calculated on the basis of the enrichment of the category (ie number of genes affected/number of genes in the category).