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. 2012 Oct 8;7(10):e46779. doi: 10.1371/journal.pone.0046779

Figure 2. Effect of Type I–III IFNs on ET-1 release from HPASMCs.

Figure 2

In the presence of TNFα, type I and type II, but not type III, interferons (IFNs) induce the release of ET-1 from human pulmonary artery smooth muscle cells (HPASMCs). Cells were treated with IFNs for 24 hours. Data are the mean ± standard error of the mean for n = 8. Within-group analysis was performed using one-way ANOVA followed by a Dunnett's post-test, where * indicates p<0.05 compared to control. Between-group analysis, for the effect of TNFα, was performed using two-way ANOVA followed by Bonferroni's post-test where # indicates p<0.05.