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. 2012 Oct 8;7(10):e46779. doi: 10.1371/journal.pone.0046779

Figure 3. Effect of native versus pegylated IFN on IP10 release from HLMVECs.

Figure 3

Effect of native IFNα2a or IFNα2b versus pegylated (PEG) forms on IP10 release from human lung microvascular endothelial cells (HLMVECs; A, B), human pulmonary artery smooth muscle cells (HPASMCs; C, D) and type II pneumocytes (A549 cells; E, F). Cells were treated with interferons (IFNs) alone (A, C and E) or in the presence of TNFα (10 ng/mL; B, D and F) for 24 hours. Data shown are mean ± standard error of the mean for n = 6 and were analysed using two-way ANOVA where * indicates p<0.05 for PEG-IFNα2a versus the other three IFNs.