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. Author manuscript; available in PMC: 2013 Oct 15.
Published in final edited form as: J Immunol. 2012 Sep 10;189(8):3983–3994. doi: 10.4049/jimmunol.1200626

FIGURE 5. DM-mediated half-life distinguishes vaccinia epitopes from non-recognized peptides in a set of predicted HLA-DR1 binders.

FIGURE 5

Binding properties of a selection of other vaccinia virus peptides predicted to bind to HLA-DR1 and shown to be recognized by a set of vaccinia-immune donors (epitopes, red) or not recognized (non-epitopes, blue). (A) IC50, (B) intrinsic half-lives, (C) DM-mediated half-lives, and (D) DM-susceptibilities of epitopes and non-epitopes were shown with p-value indicated on the right panels. DM concentration was 1uM. The IC50 and dissociation kinetics for each single peptide were listed in Table III. These data represent three independent experiments with two replicates each.