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A, B, Six hour chow intake in WT (A) and SIM1 HET (B) littermates (10 weeks) treated with d-Fen (3 mg/kg) or saline (i.p.) (n = 5–7 per genotype). Data are mean ± SEM, **p < 0.01 for d-Fen versus saline. C, Chow-fed and HFD-fed WT mice (16 weeks; n = 8–9 per group) treated with d-Fen (3 mg/kg) or saline. d-Fen-induced 1 h food intake was normalized by food intake after saline. Data are mean ± SEM.
