Figure 3. Array-wide analysis of mutp53, SP1 and ETS1 binding sites. (A) Distribution of the scores calculated for the overlap of mutp53, ETS1 and SP1 binding regions with CpG-islands and DNaseI-HS regions. The distribution was used to identify a significance threshold, where peaks with a score > = 20 are assumed to overlap significantly. (B) Venn-diagram displaying the number of overlapping mutp53, ETS1 and SP1 binding regions.