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. 2012 Oct 9;3:205. doi: 10.3389/fgene.2012.00205

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Transcriptional regulation by long ncRNA. Long ncRNAs can conduct transcriptional regulation of target genes by: (A) transcriptional interference. The purple rectangle represents the promoter region for SER3, and the blue boxes are SER3 upstream activating sequence (UAS) elements; (B) interacting with promoters. The short purple rectangle represents the minor promoter, and the long purple rectangle represents the major promoter; (C) interacting with transcriptional factors. ei and eii are two ultraconserved enhancers.