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. Author manuscript; available in PMC: 2013 Oct 1.
Published in final edited form as: Biopharm Drug Dispos. 2012 Aug 21;33(7):366–377. doi: 10.1002/bdd.1800

Table 3.

Simulated Cmax and AUC0-inf of IR ibuprofen at different intestinal pHs

An IR dose
Release Rate Default pH 0.5 lower pH 1.0 lower pH 2.0 lower pH
Cmax (μg/mL) 32.2 ± 1.3 26.6 ± 1.6 24.8 ± 1.9 13.5 ± 2.5
AUC0-inf (μg-h/mL) 89.1 ± 3.9 90.0 ± 3.5 88.4 ± 3.9 81.6 ± 5.8

Data reported as mean ± SD.