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“Off” and “on” FOG behavior according to medication condition
Abbreviations: FOG = freezing of gait; “off” = after an overnight withdrawal, with testing about 12 hours after the last dose of dopaminergic medication; “on” = approximately 45 minutes after a dose of l-dopa, once a subject recognizes his or her best response; “supra-off” = after more than 70 hours without any medication; “supra-on” = 45 to 60 minutes after intake of 200% of the regular or “therapeutic” l-dopa dose.
