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Effect of FK506 on cccDNA in HepG.2.2.15 cells. Control: DNA extracted from HepG2 cells as negative control. Lane 1: PCP10-purified plasmid as positive control. Lanes 2–4: HepG.2.2.15 cells treated with FK506 at concentrations of 50 μg/L, 100 μg/L, and 500 μg/L, respectively.
