Skip to main content
. 2012 Oct 2;7(10):e44479. doi: 10.1371/journal.pone.0044479

Figure 5. Intra-group epigenetic distances for the promoters of BRCA1, BRCA2, HTT, DMPK1, PSEN1 and PSEN2 genes.

Figure 5

This distance represents the net dissimilarity of DNA methylation profiles between two sequences: the higher the distance, the more dissimilar are the compared samples. Different individuals were crossed with each other and Euclidean distances were calculated for beta-values of CpG sites as a marker of inter-individual variability in three different sperm subpopulations: A) Whole sperm population; B) swim-down and C) swim-up fractions. Numbers on the X axis indicate the identity of the pair-wise comparisons inside the experimental group: individuals EC01, EC07, EC10, EC12, EC14, EC16, EC18 and EC10 are numbered 1 to 8. Distance values are displayed on the Y axis. The top and bottom blue guidelines represent the 0.025 and 0.975 quartiles, while the red guideline represents the mean distance value.