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. 2012 Jun 20;32(25):8633–8648. doi: 10.1523/JNEUROSCI.0556-12.2012

Figure 1.

Figure 1.

Quantification of LC3 and p62 levels in the presence or absence of bafilomycin A1 in cultured WT-ES, PS1ko-ES, and PSdko-ES Cells. A, LC3 levels detected by Western blotting. B, Quantification of LC3 II levels normalized to actin (*p < 0.06, **p < 0.01, ***p < 0.05, n = 3). C, Autophagic flux of LC3II in WT-ES, PS1ko-ES, and PSdko-ES cells. D, p62 levels detected by Western blotting. E, Quantification of p62 levels normalized to actin (*p < 0.01, **p < 0.01, ***p < 0.05, n = 5). F, Autophagic flux of p62 in WT-ES, PS1ko-ES, and PSdko-ES cells. G, Detection of PS1 expression in WT-ES, PS1ko-ES, and PSdko-ES cells. H, Detection of PS2 expression by RT-PCR in WT-ES, PS1ko-ES, and PSdko-ES cells.