. 2012 Jun 22;40(18):e143. doi: 10.1093/nar/gks601

Table 2.

In vitro half-lives and initial compositions of unstable and stable DPCs induced by aldehydes and C-ion beams

Agents	Half-life (h)		Composition (%)		Apparent half-life (h)^a
	Unstable	Stable	Unstable	Stable	In vitro	In vivo	Ratio
Aldehydes
ACR	5.4	26.9	23.8	76.2	18.2	8.2	2.2
CAA	5.4	26.6	26.7	73.3	17.0	7.5	2.3
CRA	2.4	23.9	16.1	83.9	17.9	8.4	2.1
GA	5.3	24.1	12.1	87.9	20.2	7.2	2.8
FA	6.8	103.5	90.4	9.6	8.0	4.8	1.7
PEN	6.6	54.1	59.6	40.4	12.4	5.7	2.2
Ionizing radiation
C-ion	10.7	3.5 × 10⁴	40.1	59.9	–	–	–

^aApparent in vivo and in vitro half-lives for aldehydes were determined from Figures 3 and 4, respectively. In vitro half-lives for C-ion beams were determined from Figure 7B. The ratio indicates the value of apparent in vitro half-life/apparent in vivo half-life.