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Large- and regular-sized exosomes; and nucleosomes have different proteins. (A) Fractions of 6- and 90-h gradients of P70s from MDA-MB-231 cells were probed for protein markers using quantitative dot-blot; or by western blot analysis for acetyl-H3 histone. (B) Quantitation of data in (A). (C) Comparison of abundance of exosome and L-exosome-associated antigens. *P < 0.05; **P < 0.01; ***P < 0.001, (n = 4). Bars represent standard deviation.
