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. 2012 Jul 11;40(18):8927–8941. doi: 10.1093/nar/gks659

Figure 2.

Figure 2.

Global expression profile of Spi-1-modulated genes. (A) shSpi-1-A2B (similar expression levels were observed in shSpi-1-A2C cells) and control cells were cultured with (26 h, 44 h and 96 h) or without dox (26 h and 44 h), and the extracted proteins were analyzed by western blotting using Spi-1 and adaptin antibodies. Two bands corresponding to Spi-1 were detected. (B) Ingenuity Pathway Analysis (IPA) of Spi-1 target genes. IPA was performed on Spi-1 activated and repressed genes as identified using expression microarrays. The 10 most significant molecular and cellular functions revealed are shown and -Log (Bonferroni–Holm P-value) are indicated. The orange bar represents the P-value threshold of 0.05 (-Log (P-value) = 1.3).