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. 2012 Jul 11;40(18):8927–8941. doi: 10.1093/nar/gks659

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© The Author(s) 2012. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 6. — Properties of the ChIP-seq peaks in primary erythroleukemic cells. (A) Distribution of the number of ChIPMunk-defined Spi-1-motif hits per Spi-1 peak sequence in the promoters + ImDown subregions (all peaks) or peaks in the promoter + ImDown subregions that contain (with CGI) or not (w/o CGI) CGIs and according to Spi-1 transcriptional activities. The red square indicates the mean, and the black line inside the box plot indicates the median. The Wilcoxon test was used to statistically examine the differences in the distributions of the number of Spi-1-motif hits. P < 0.05 was considered statistically significant. (B) Distribution of the Spi-1 peak heights in the promoter + ImDown subregions (all peaks) or peaks in the promoter + ImDown subregions that contain (with CGI) or not (w/o CGI) CGIs according to Spi-1 transcriptional activities. The red square indicates the mean, and the black line within the box plot indicates the median. The Kolmogorov–Smirnov test was used to statistically examine the differences in the distribution of the Spi-1 peak height compared with the peaks in the NoResp group of genes; P < 0.05 was considered statistically significant.