Table 5. Cerebral sites of maximal hemodynamic responses during speech production (SP): Main effects (p_uncorrected<0.001, k≥10) of L-dopa medication states.

			off L-dopa					on L-dopa
Cerebral area	BA	L/R	x	y	z	Z-score	k	x	y	z	Z-score	k
Precentral gyrus	4	L	−46	−15	39	4.06	95°	−46	−15	39	4.29	94∧
Precentral gyrus	4	R	41	−12	33	4.67	58	41	−12	28	4.09	36*
Medial frontal gyrus	6	L	−6	−6	55	4.97	123#	−3	−15	57	3.97	27
Postcentral gyrus	2	L	−35	−21	33	4.40	95°	−38	−21	28	4.32	94∧
Postcentral gyrus	2	R						36	−18	30	4.07	36*
Anterior cingulate gyrus	24	L	−6	0	47	4.63	123#	−6	5	42	3.94	33
Supramarginal gyrus	40	L	−40	−47	32	3.71	33	−11	−64	−19	3.73	10
Cerebellum (dentate)		L						−11	−64	−19	3.73	10
Cerebellum (hemisphere)		L	−25	−62	−27	5.79	149	−27	−62	−27	4.01	10
Cerebellum (hemisphere)		R	26	−64	−25	5.25	118	26	−64	−25	4.07	17

Cerebral activation locations refer to maximal hemodynamic response sites. L/R: left/right; BA: Brodmann’s area; x, y, z: mediolateral, rostrocaudal and dorsoventral Talairach coordinates; k: cluster size (number of voxels); °/^#/^∧/* : parts of the same cluster.