Table 3. Ascorbic acid content, total antioxidant status, carbonyl content and malondialdehyde levels in TP53 p.R337H mutation carriers and non-carriers with positive (PPH) and negative (NPH) personal histories of cancer.
Non-carriers | P | Carriers | P | |||
NPH (n) | PPH (n) | NPH (n) | PH (n) | |||
Ascorbic acid content (mM) | 3.90±0.21(11) | 3.61±0.16(5) | 0.370 | 2.39±0.19(11) | 2.21±0.22(5) | 0.583 |
TAS (mmol/L) | 1.34±0.05(11) | 1.22±0.08(5) | 0.232 | 1.47±0.04(12) | 1.47±0.10(4) | 0.936 |
Carbonyl content(nmolcarbonyl/mg of protein) | 0.20±0.06(10) | 0.30±0.09(4) | 0.419 | 0.52±0.13(8) | 0.32±0.14(3) | 0.408 |
Malondialdehyde levels(mmol/L) | 40.09±0.93(11) | 40.44±1.44(5) | 0.827 | 159.6±1.04(11) | 161.7±1.08(5) | 0.316 |
Data are presented as mean ± S.E.M.