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. 2012 Oct 9;7(10):e46568. doi: 10.1371/journal.pone.0046568

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This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

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Administration of TNF to rats resulted in significant increases in superoxide and hydrogen peroxide production rates. Losartan attenuated these changes. * p<0.05 vs. control; $ p<0.05 vs.TNF.