Table 1. Main characteristics of studies included on platelet activity tests in the meta-analysis.
First author | year | ethnicity | population studied | treatment protocal | definition of case | case | control | HWE | ||||
CC | CT | TT | CC | CT | TT | |||||||
Spiewak, M. [10] | 2009 | NA | ACS treated with PCI | LD aspirin 300 mg clopidogrel (300 mg or 600 mg)MD aspirin 75 mg clopidogrel 75 mg qd | collagen/adenosine diphosphate (CADP)-CT<130s | 4 | 16 | 10 | 23 | 34 | 11 | 0.791 |
Kim, I. S. [12] | 2012 | Asian | Patients treated with PCI | cilostazol 100 mg bid, clopidogrel 75 mg and aspirin 200 mg qd | 5 mol/l ADP-induced maximal PR (Aggmax)>46%. | 7 | 4 | 1 | 45 | 58 | 12 | 0.287 |
Jeong, Y. H. [13] | 2010 | Asian | AMI treated with coron ary angiography or PCI | MD clopidogrel 150 mg aspirin 200 mg qd | 5 mol/l ADP-induced maximal PR (PRmax)>50%. | 13 | 14a | 56b | 55b | 15b | 0.791 | |
Jeong, Y.H. [14] | 2011 | Asian | AMI treated with PCI | LD aspirin 300 mg clopidogrel 600 mgMD aspirin 100–200 mg clopidogrel 75 mg | 20 mol/L ADP-induced maximal PR(PRmax)>59% | 64 | 54 | 16 | 60 | 54 | 18 | 0.303 |
LD: loading dose; MD: maintenance dose; HWE: Hardy-Weinberg equilibrium.
the number is consisted of CT and TT.
the number is consisted of case group and control group.