Table 1.
Baseline characteristics of recurrence cases and controls, men who underwent radical prostatectomy for clinically localized disease at Johns Hopkins Hospital, 1993–2001
| Recurrence cases | Controls | P | |
|---|---|---|---|
| N | 484 | 484 | |
| Mean ± sd age (years) | 58.9 ± 6.2 | 59.0 ± 5.9 | Matched |
| Race (%) | |||
| White | 85.1 | 88.0 | |
| African-American | 9.5 | 7.9 | |
| Hispanic | 1.5 | 0.6 | |
| Asian | 0.4 | 0.0 | |
| Other | 3.5 | 3.5 | Matched |
| Mean ± sd pre-operative PSA (ng/mL) | 12.0 ± 9.5 | 10.9 ± 8.4 | 0.05 |
| Pathological stage (%) | |||
| T2 | 13.8 | 13.6 | |
| T3a | 51.5 | 51.5 | |
| T3b or N1* | 34.7 | 34.9 | Matched |
| Pathologic Gleason sum (%) | |||
| 5 | 0.6 | 0.6 | |
| 6 | 14.3 | 14.5 | |
| 7 | 61.2 | 63.0 | |
| 8+ | 24.0 | 21.9 | Matched |
| Positive surgical margins | 35.3 | 21.1 | <0.0001 |
| Mean year of surgery | 1997 | 1995 | <0.0001 |
*
18.6% of cases and 13.0% of controls had lymph node metastases